The S3E – Southern European Entrepreneurship Engine consortium is excited to announce the launch of its second Open Call for the S3E program the EU-funded initiative fostering Deep Tech entrepreneurship in South European countries. 

After launching the first Open Call in 2022, the S3E Program is coming back this year to keep supporting startups, researchers, tech transfer offices, corporates and SMEs in Southern Europe developing innovative deep tech solutions with social and sustainable impact at their core.

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Who can join the S3E Program?

The S3E Accelerator Program is built around 3 tracks of bespoke services, tailored to the needs of different groups operating within the deep tech innovation ecosystem.

  • S3E Start: helps research teams and tech transfer offices to explore the commercial viability of their deep tech projects.
  • S3E Charge: supports deep tech startups in their growing phase that want to improve their business model and learn how to access dilutive and non-dilutive funding.
  • S3E Reverse: connects corporate challenges with solutions developed by scaleups and SMEs thanks to our Brokerage Program, based on a successful open innovation methodology. 

The S3E Program welcomes applications from the following countries:

  • South European countries: Bulgaria, Croatia, Cyprus, Greece, Italy, Malta, Portugal, Romania, Slovenia, and Spain. 
  • Associated countries: Albania, Bosnia and Herzegovina, Montenegro, North Macedonia, Serbia, Kosovo and Turkey.

Applications for the S3E Open Call #2 will officially open for the three tracks on 18 September 2023. We encourage those interested in applying to you will receive a reminder on the day so you won’t miss out!


We look forward to creating long-lasting collaborations!

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