The wait is finally over! The S3E – Southern European Entrepreneurship Engine consortium is excited to announce the official launch of the second Open Call for the three tracks of the : Start, Charge & Reverse.

S3E is the ultimate program of support for entrepreneurs in Southern Europe developing Deep Tech solutions with social and sustainable impact at their core. Each track is dedicated to three main groups operating within the innovation ecosystem: researchers and TTOs working on a project as a team, startups at their growth stage, and corporates interested in joining forces with scaleups/SMEs.

The S3E Charge program has been an invaluable experience. The theoretical sessions and mentorship have greatly supported our growth and have improved the key strategies to effectively communicate our value proposition. We highly recommend this program to other entrepreneurs, as it provides the necessary tools and connections for success in the Deep Tech industry.

Naeria Navarro Navarro CTO, Fresh Water Nature SL – Charge Startup

What’s the difference between the 3 tracks?

  • S3E Start: helps research teams and tech transfer officers to explore the commercial viability of their deep tech projects. Through an 18-week online training & mentorship program, the selected research teams will learn first-hand about the processes required to develop a business case for science-based products or services.
  • S3E Charge: supports deep tech startups in their growing phase that want to improve their business model and learn how to access dilutive and non-dilutive funding. Over 14 weeks, the selected startups will receive tailored mentorship to guide them through the validation process of their product or service, and the creation of an investment-ready business plan. 
  • S3E Reverse: connects corporate challenges with solutions developed by scaleups and SMEs thanks to our Brokerage Program, based on a successful open innovation methodology. To access the first phase of this track, large companies and public organisations have to submit a deep tech challenge.

You can find all the relevant information about each track on the section on our website.

How to apply

Those interested in joining the S3E Program need to follow these steps:

  1. Read all information about the S3E Program to decide which track best suits you
  2. Once you know which track you want to apply to, download the relevant track Guidelines for Applicants and the Open Call Text via Zenodo: +
  3. After carefully reading the mandatory documents, you can now complete your application via the F6S online platform: S3E Charge application for Startups + S3E Start application for Researchers + S3E Start application for Tech Transfer Offices

The S3E Open Call #2 welcomes applications from the following countries:

  • South European countries: Bulgaria, Croatia, Cyprus, Greece, Italy, Malta, Portugal, Romania, Slovenia and Spain. 
  • Associated countries: Albania, Bosnia and Herzegovina, Montenegro, North Macedonia, Serbia, Kosovo and Turkey.

The S3E Start program has a comprehensive curriculum that provided us with the necessary information on deep-tech commercialization. With the TEC sessions, webinars and mentor meetings, we had the chance to learn from experts. The S3E team has been very supportive and answered all the questions we had. We strongly recommend this program.

Elif Begum Elcioglu NANO INK – Start Researcher

Key dates to keep in mind

  • 18 September 2023 (12pm CET):  The S3E Open call officially launches for the 3 tracks: S3E Start, S3E Charge and S3E Reverse
  • 15 December 2023 (5pm CET): Deadline for applying to S3E Charge (startups) and S3E Reverse (large organisations acting as ‘Challengers’)
  • 12 January 2024 (5pm CET): Deadline for applying to S3E Start (research teams & tech transfer officers)

Join our upcoming S3E Info Webinars!

To help this year’s applicants prepare for their submissions, the teams behind S3E Start & S3E Charge will be hosting a series of Q&A Webinars. These sessions provide an open space to everyone interested in applying to ask any questions they may have about the S3E Program — we highly encourage future participants to come along!

Check the available dates for S3E Start and S3E Charge and book your preferred session via Eventbrite. The earlier you join one of our Info Webinars, the more time you and your team will have to prepare before submitting your application.

Got any questions?

Check the FAQs section on our website, where you fill find an extensive list of answers regarding the S3E Program. If you would like to speak directly to someone from the S3E team, you can email us at info@south3e.eu


We look forward to creating long-lasting collaborations!

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