Mission accomplished: South3E wraps up having successfully contributed towards the Southern European deep tech ecosystem
The South3E project has now approached the end of its mission. It has dedicated the last two and a half years to helping forge a stronger deep tech innovation ecosystem in the South of Europe.
After launching in June 2022 and officially wrapping up in December 2024, the four partners of the South3E Consortium are now celebrating the successes achieved by the project and its three tracks, as reflected in its numbers.
https://youtu.be/b7Dn0VzmkSs
South3E in numbers
S3E START
The hands-on program for research teams to help them explore the commercial viability of their deep tech projects, led by HiSeedTech.
Results of this track:
- 2 Open Calls
- 60 Applications received from research teams
- 31 Applications received from TTOS
- 17 Evaluators
- 34 Selected research teams
- 23 Selected TTOs
- 46 mentors
- Training sessions delivered: 30 online tutorials, 14 webinars
- 2 Open Days with 481 registered participants
🌟 Highlighted achievement: S3E Start received a Net Promoter Score (NPS) of 53, which reflects the high satisfaction among the participating teams.
S3E CHARGE
The acceleration program for growth startups to access funding opportunities and expand their business operations, led by Institute for Sustainable Development at EPLO.
Results of this track:
- 3 Open Calls
- 92 Applications received
- 16 Evaluators
- 50 Participating startups
- 39 Training Sessions delivered
- 37 mentors
- 2 Open Days with 240 registered participants
🌟 Highlighted achievement: Thanks to S3E Charge, the participating startups have been successfully connected to 50+ public and private funding opportunities.
S3E REVERSE
The business brokerage program connecting deep tech SMEs and startups with corporates to tackle industry challenges, led by International Development Ireland.
Results of this track:
- 2 Open Calls
- 29 Corporate challenges
- 98 Solvers applications
- 24 Solvers selected
- 25 deep tech Brokers
- 71 successful matches
🌟 Highlighted achievement: The outcomes of the Reverse Brokerage program will help to drive the growth of open innovation and corporate venturing in Southern Europe.
None of this would've been possible without the amazing S3E community we've built over the past 2 years!
We'd like to express our heartfelt thanks to all the S3E Experts that embarked with us on this journey, including mentors, evaluators, assessors and trainers. And, of course, to the European Innovation Council and SMEs Executive Agency (EISMEA) for supporting our initiative.
S3E Start showcases the innovative deep tech projects from Southern Europe in a magnificent Open Day in Lisbon
On June 18th, the S3E team celebrated a hybrid Open Day in Lisbon to showcase the , the program that provides expert support to research teams and technology transfer officers in Southern Europe.
Watch the summary video!
https://youtu.be/AvonR5QPkxA
The S3E Start Open Day took place at the iconic BBVA Tivoli Theatre with approximately 60 people attending in person. The full 3-hour event was also livestreamed, reaching over 230 participants from across the European deep tech ecosystem who registered to join remotely. The audience included member companies from HiSeedTech (the S3E team who facilitated the event), international investors, business angels, innovation hubs, higher education representatives, corporates, researchers and deep tech enthusiasts.
The event kicked-off with a warm welcome from Mario Freire, President of the Board of HiSeedTech, which is the coordinator of the S3E – Southern European Entrepreneurship Engine project. Freire's introduction was followed by Daniel Gassman, Head of Sector Ecosystems and Prizes at the European Innovation Council and SMEs Executive Agency (EISMEA), who joined online to introduce the context where S3E stands, highlighting the main objectives of the New European Agenda and how the S3E project is working towards creating long-lasting impact by supporting deep tech research, innovation and entrepreneurship in Southern Europe.
Pedro Vilarinho, technical coordinator of the S3E initiative, took the stage to provide an overview of the S3E Start program, reflecting on its goals, milestones, and the remarkable progress made during the second cohort of research teams who joined the program in January. In the 2024 edition, S3E Start has supported 14 research teams in total, involving more than 60 researchers and 10 technology transfer officers from 12 different countries. The program also counted on the support of 30 mentors pooled from our community of S3E Experts.
The whole session, hosted by Roger Debo, consisted on 14 pitches from the finalist research teams, alternating onsite and online presentations, where the researchers explained the purpose and progress of their inspiring and significant work. Debo also delivered an inspirational talk on deep tech entrepreneurship.
The S3E Start Open Day showcased the remarkable potential of innovation in deep tech in Southern Europe, marking the culmination of 20 weeks of diligent effort by the 14 research teams participating in the S3E Start program. A huge congratulations to everyone involved for making this such a successful event!
The full recording of the S3E Start Open Day is now available to watch here.
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EPF3Bio: meet the team behind TriPhyte, a technology to cultivate a greener, healthier world
EPF3Bio, led by researchers from National and Kapodistrian University of Athens (Greece), is one of the supported research teams in the first S3E Start Programme.
Agriculture and food security programs face several challenges, largely stemming from yield loss as a result of pests, diseases and soil degradation. The mitigation of these phenomena relies on chemical applications with high environmental and climate costs, while their intensive application over several decades has contributed to abundant pesticide resistance that furthers damages. As such, recent EU directives require reductions in chemical control, and place greater emphasis on environmentally friendly biotechnology solutions.
The technology developed by EPF3Bio addresses all of the above, offering a sustainable alternative to dealing with Europe’s pesticide problem and the biodiversity crisis. TriPhyte is a biological fungal-based all-in-one product that functions on three essential dimensions: biofertilizer, biocontrol agent and biostimulant. Extensive research has shown its ability to increase crop yield by 20% while protecting plants from pests and diseases. Apart from the simplicity of its application, TriPhyte combines three products into one, which makes it remarkably cost-effective compared to other organic agriculture products.
Their technology is suitable for both farmers and small-scale growers who want to switch to sustainable farming and/or enter into the organic market, guaranteeing the health of consumers and farmland.
Learn more about EPF3Bio by watching the pitch done by researcher Marios Andrikopoulos during the Start Open Day on 20th July 2023.
https://youtu.be/avKRvpls3X4
Would you like to get in touch with them? Let us know! Email us at info@south3e.eu
Looking forward to exploring synergies and creating a long-lasting collaboration.
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S3E at WARM, the Worldwide Accelerators Rally at Matosinhos
WARM, the Worldwide Accelerators Rally at Matosinhos is an event that brings together innovation acceleration programs, incubators and TTOs with investors, companies, and startups.
This year edition was organized by RESOLVE-Health. RESOLVE-Health is a technology-based acceleration program designed to provide support and management tools to early-stage projects and start-ups in the health sector, focused on transforming innovative research into profitable ventures. The aim is to foster knowledge transfer, ultimately leading to licensing patents or launching start-ups. This is done by teams of researchers and entrepreneurs involved in this area. RESOLVE-Health is an initiative from I3S - Institute for Innovation and Research in Health in Porto.
WARM goal was to foster a collaborative movement in the health innovation ecosystem and took place on May 25, at Terminal de Cruzeiros do Porto de Leixões, in Matosinhos.
Our team member HiSeedTech had the opportunity to participate and present the S3E program with the focus on S3E Start and share some testimonials of researchers that have already been impacted by our methodology during the panel "Testimonials from Teams Supported by Acceleration Programs!". Claudia Barbosa, S3E Project Coordinator received valuable feedback from the audience and especially from researchers who have seen a change in their lives and the way they look at science, which was truly inspiring. Claudia invited the more than 100 participants to join the S3E community and to be alert for the upcoming Open Call after summer, which will bring new opportunities for researchers and startups from Southern Europe to bring their deep tech ideas into the market.
More info about the event: click here,
Looking forward to exploring synergies and creating a long-lasting collaboration.
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Five projects, one mission: Expanding Acceleration Ecosystems in the European Union
Five projects, one mission: Expanding Acceleration Ecosystems
Incubators, accelerators and different types of ‘company-builders’ play a crucial role in providing start-ups with growth support. Due to the diverse innovation landscape in Europe, start-ups from better-connected innovation ecosystems benefit from more local accelerators with greater funding opportunities and more qualified business support services compared to their counterparts elsewhere.
This geographical gap often requires start-ups from less connected ecosystems to move to more established hubs elsewhere in Europe. Consequently, there are fewer scale-ups in less connected innovation ecosystems, creating unbalanced business activity and employment opportunities. The European Commission, launched the ‘Expanding Acceleration Ecosystems’ mission, as part of the European Innovation Ecosystems (EIE) work programme, with the purpose to reverse this flow by making ‘modest’ and ‘moderate’ innovation ecosystems more attractive to international companies interested in setting up their businesses outside the established centres and tapping into the potential of local ecosystems.
In light of this, around one year ago, five projects kicked off to support the European Commission fulfil this mission: sharing business acceleration related best practices, knowledge, tools and methods; exchanging promising start-ups and SMEs; exchanging accelerator programme experts; establishing links between local actors in developing ecosystems, among others, and one of these projects is S3E – The Engine for South European Deep Tech.
S3E has developed an engine of growth to contribute to improving the connectedness and efficiency of the southern European countries’ innovation ecosystems. Our focuses on the acceleration of deep tech research projects, growth startups and scaleups, contributing to closing the innovation gap between these countries and more advanced innovation ecosystems. S3E is supporting south European innovators to develop into deep tech and procure funding for the early stages of development through three innovation programmes: START, CHARGE and REVERSE.
However, S3E is not alone in this mission and four other projects were selected with complementary action plans to expand acceleration ecosystems. Let’s discover them in this blog’s post!
AccelerAction: A pan-European Networked Acceleration Programme to expand acceleration ecosystems and foster the scalability potential of European business
The diverse innovation landscape in Europe and the geographical gap among the "innovation leaders" and the less-connected ecosystems highlights that the latter suffer from weaker entrepreneurial activity and scarcer investments. The EU-funded AccelerAction project aims to improve the quality and outreach of business acceleration services in weaker innovation ecosystems in the field of DeepTech by creation of new pan-European Networked Acceleration Programme (EU-NAP) that will be tested in 3-months blended exchange programme for 10 promising start-ups with special focus on gender dimension. To its end the project will encourage entrepreneurial activities, stimulating cooperation among innovation actors generating alliances and strengthening less connected ecosystems to increase their competitiveness & connectivity also thanks to the creation of the virtual platform with match-making feature.
ACCELERO: Accelerating Local Innovation Ecosystems in Europe
ACCELERO has the ambition of creating a pan-European community of business support organisations (BSOs) as the onestop shop for all BSOs and its “customers”, the startups and SMEs, as well as for peer-to-peer exchange, networking and connectedness for all stakeholders engaged in the broader innovation ecosystem. This will be achieved with an initial ACCELERO extended community apart from consortium members to co-create and pilot-test high-quality business acceleration services with European BSOs from emerging and moderate innovators together with experts from strong and leader innovation regions or Member States, followed by the launch of the community inside Euroquity platform.
Food-scalEUp: Expanding the European digital agri-food acceleration ecosystem
Expanding the European agri-food digital innovation ecosystem’s capacity is a priority for 10 organisations that form Food-scalEUp, an EU-funded project that is focusing on emerging and moderate innovator regions. Its objective is to help these innovator regions become better connected, effective, impactful, resilient and recognised around the globe. To succeed, it will develop optimal business acceleration services in agri-food digital innovation ecosystems; foster connections and transfer knowledge regionally and beyond; and balance the capacity of agri-food digital innovation and acceleration ecosystems in the regions in question.
BEYOND: Boosting pan-european Exchange between acceleration ecosYstems for improving quality and Outreach of business acceleration services in Developing innovation ecosystems
Introducing the new Virtual Accelerator Marketplace (VAM), designed to support joint business accelerator activities for Europe’s startups. It also aims to advance investment flows from net contributor regions towards ‘modest’ and ‘moderate’ ones. Developed by the EU-funded BEYOND project, VAM will test a self-sovereign digital identity scheme (funding passport) available to startups independent of which accelerator they join. Moreover, a joint platform will allow online acceleration and provide a framework for the efficient development of startups. BEYOND will also focus on sharing specific offers from the different project participants and resources; it will develop an incentive structure where all partners benefit from high-quality startups developing their services, and create a cross-region marketplace for fundraising.
Looking forward to exploring synergies and creating a long-lasting collaboration.
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S3E CHARGE acceleration program kicks-off to support growth startups
S3E team kicked off the CHARGE Acceleration program with an onboarding session with the growth startups selected through the Open Call #1.
The growth startups introduced themselves and their deep tech innovations. They all had the chance to meet each other creating a perfect atmosphere for collaboration, networking and opportunities to grow. During the following 14 weeks, S3E team and the assigned Mentors will be supporting the selected participants defining their business plans and go to market strategies.
About S3E CHARGE acceleration program
S3E Charge offers a 14-week tailor-made mentoring and networking program to develop an investment-ready business plan and support the access to non-dilutable and dilutable funding.
The mentoring process will guide the growth start-up teams in the development of a business plan for a product, service or process that makes them investment ready and takes their validated business case to an investor attractive level. So, they will acquire skills in technology commercialisation, science-based entrepreneurship, business development and intellectual property protection using their own business offerings through tailor-made mentorship.
When the selected startups finish the program, they will have developed a business plan for a product, service or process and acquired skills and be investment ready to:
- link their product/service/process product with market needs,
- better communicate their offerings to potential clients and investors,
- become market ready to pitch, persuade and readapt their business offerings to different audiences, depending on market needs
- connect to ‘Innovation Leaders’ and ‘Strong Innovators’ Ecosystems
- better understand to protect IP
- prepare an investment ready business plan
- get access to funds and funding
The outcome of the S3E Charge will better position them to apply for public or private funding and programs, because it will help them link their business offerings to market needs and become market ready to pitch and attract investments whilst having validated and honed your business plan and your value proposition.
Stay tuned for further communications!
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S3E START acceleration program kicks-off to support deep tech researchers
S3E team kicked off the START Acceleration program with an onboarding session with the 16 research teams and tech transfer offices selected through the Open Call #1.
The research teams presented their deep tech innovations and the tech transfer offices their research work. They all had the chance to meet each other creating a perfect atmosphere for collaboration and networking opportunities. During the kick off meeting, held virtually, we celebrated the first webinar of the training series called “War Stories'' with Joana Simões Correia and Thiago Gomes, former participants of the HiEngine program that inspired S3E START.
Joana Simões Correia is a co-founder and the Executive Director of Exogenus Therapeutics. With a PhD in Human Biology, she dedicated more than 15 years of her career to research in the area of human diseases, including cancer genetics and regenerative medicine. Author of several high impact papers and patents, she has been a pioneer in exploring the therapeutic potential of umbilical cord blood derived exosomes as a therapeutic tool. Since 2015 she has been leading Exogenus Therapeutics research and development team and activities and has been recognized several times for the excellence of her work, nationally and internationally (eg. ANJE Young Entrepreneur Award 2015, Everis Foundation Award 2016, Prémio Empreendedor XXI 2019). Under her leadership, Exogenus Therapeutics has conquered a distinguished position in the field and is recognized has a leading company harnessing the potential of exosomes as a therapeutic tool for diseases of high unmet need.
Thiago Gomes is the Co-Founder & CEO of a StartUp called BioReboot. BioReboot is a Startup that focuses on reusing and transforming agricultural waste into a biomaterial that has the potential to replace single-use plastics in the agriculture sector. It was the winner of the StartNOW 2020 acceleration program powered by StartUP Madeira. It represented the Autonomous Region of Madeira in the first phase of Climatelaunchpad 2021, the Global Green Business Ideas Competition. Currently, it represents the University of Madeira in the Born from Knowledge 2021 Competition.
Joana and Thiago gave participants an inspirational speech about their drive to be entrepreneurs, their successful experiences, sharing advices and learning, and the reasons behind their participation in the program that inspired S3E START.
During the following 18 weeks, S3E team and the designed Mentors will be supporting the selected participants defining their pathways from the lab to the market.
About S3E START acceleration program
The S3E Start includes online classes (mainly on the topics related to the development of a business case for deep tech projects) and webinars (on diverse topics pertinent to the development of the relevant skills). These in-class tutorials will account for less than half of the total workload of the Program, the remaining time being allocated to group meetings facilitated by the mentors. There are deliverables to be fulfilled each week and these deliverables will guide the participants throughout the three phases of the Program, namely:
IDEATION PHASE: In this phase a set of clearly defined product concepts will be developed and prioritized considering the linkages between the unique capabilities of the technologies and customer/market needs (Technology-Product-Market linkages). Each team is required to generate multiple product concepts that can be enabled by each technology. Then research teams will have to identify diverse market opportunities for each product concept to further specify product attributes.
DEVELOPMENT PHASE: In this phase teams will refine, improve, validate and select among the product concepts devised in the ‘ideation’ phase using a guided approach that will force them to contact the ‘market’ to challenge and sustain each of the T-P-M linkages proposed in the ideation phase. In the early stages of this phase, teams will be looking for ‘fatal flaws’ (product or market) that will justify ‘dumping’ one (or more) T-P-M linkage(s). With the information gathered from the market teams will develop “value propositions” for their products using a standard format that will force them to (i) clearly define the product, (ii) tie customer needs to the benefits of using the product in economic terms and (iii) differentiate the product from competitors based on unique product features. Additionally, they will build a business model that, for the product moving forward, describes the rationale of how the company will create, deliver, and capture value. Throughout this phase participants will have to use a set of management tools (e.g., 5 Forces Analysis, SWOT Analysis, Industry Mapping, “Voice of the Customer”, etc.) to gain a much better understanding of the way the market works and will be supported by the tools embedded in the approach, thus fine-tuning their product concept choices.
COMMERCIALIZATION PHASE: In this phase teams put the pieces of the puzzle together by building a strategy to bring the product to market. This phase begins with the definitions of the pricing point and the sales plan answering strategic questions such as market traction and market entry point(s). Additionally, drawing on the business model previously designed teams will define their development roadmap that will allow them to build the financial projections and risk analysis. At this stage teams will have all the elements needed to produce a business case and a final pitch that will be the final deliverables for the Program.
Stay tuned for further communications!
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S3E CHARGE: meet the selected growth startups
S3E CHARGE Open Call results are out!
Between November 7, 2022 and February 10, 2023, growth startups from South European countries submitted their deep tech innovations to the S3E Open Call #1 to participate in our S3E CHARGE Program.
S3E CHARGE is a program that we have designed for growth start-ups with deep tech products, services, or process concepts, grounded in a scientific discovery or meaningful engineering innovation and at a growth development stage, that are already in the market. The program will facilitate selected growth startups to be better aligned with Horizon Europe’s goals, namely by better positioning them to apply for public or private funding and programs, assisting them in linking their business offerings to market needs and becoming market ready to pitch and attract investments whilst having validated and honed their business plan and value proposition.
During the open call period, we received a total of 33 applications and after running and independent evaluation process (counting on external experts) we are very excited to share the selected growth startups that will take part in the first edition of our S3E CHARGE program.
12 GROWTH STARTUPS INVOLVED
| Project name | Team member | Country | Science field | SDG |
| RespiBit | Christodoulos Spagakas | Greece | Medical and health sciences | Good Health and Well-Being (SDG 3) |
| Distinkt | Luca Venza | Spain | Engineering and technology | Industry Innovation and Infrastructure (SDG 9) |
| Grawindy Renewable Energy INC. | Atilla Öztürk | Turkey | Engineering and technology | Industry Innovation and Infrastructure (SDG 9) |
| Bluana Foods | Florin IRIMESCU | Romania | Other | Good Health and Well-Being (SDG 3) |
| Inteligg Private Company (P.C.) | Christos Ioakeimidis | Greece | Engineering and technology | Sustainable Cities and Communities (SDG 11) |
| Digital Bites | Theodoros Sofianos | Greece | Engineering and technology | Industry Innovation and Infrastructure (SDG 9) |
| Psychomeasure | EDUARDO SAMPAIO | Portugal | Medical and health sciences | Good Health and Well-Being (SDG 3) |
| ThetaBiomarkers | Olga Begou | Greece | Medical and health sciences | Good Health and Well-Being (SDG 3) |
| Water2Wk | Juan Suárez | Spain | Medical and health sciences | Sustainable Cities and Communities (SDG 11) |
| Freshwater | Naeria Navarro | Spain | Engineering and technology | Sustainable Cities and Communities (SDG 11) |
| IIO
Arcan |
Pasquale Bombino
Ilaria Pigazzini |
Italy
Italy |
Engineering and technology
Engineering and technology |
WHAT NEXT?
S3E CHARGE offers selected growth startups a 14-week tailor-made mentoring and networking program that aims to provide skills to growth startups to enable them to:
- link the product/service/process product with market needs,
- better communicate their offerings to potential clients and investors,
- become market ready to pitch, persuade and readapt the business offerings to different audiences, depending on market needs
- connect to ‘Innovation Leaders’ and ‘Strong Innovators’ Ecosystems
- better understand to protect IP
- prepare an investment ready business plan
- get access to funds and funding
We congratulate the selected participants and we are looking forward to supporting their deep tech projects!
Deliverable 4.1. Implementation & Deployment of the S3E framework
Deliverable 4.1. Implementation & Deployment of the S3E framework
Submission date: 20 March 2023
The purpose of this deliverable is to present the S3E framework that includes all processes, tools and activities that were designed and are being implemented as part of our Engine programme. In essence, the document is a reference guide with explanations and references to all other documents that have been prepared as part of our project.
Its aim is to serve as a guide in the implementation of our Engine programme.
This Deliverable concludes the results of T4.1 (Connect) and continues with T4.3 (Boost). It will offer to test and pilot the use of the basic features for S3E users to deploy the offered services.
Looking forward to exploring synergies and creating a long-lasting collaboration.
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S3E Open Call #1 Reverse for solvers: startups and SMEs with deep tech solutions
We are looking for deep tech startups and SMEs to respond to the 15 identified challenges
The EU-funded project South3E launches a new Open Call to identify deep tech based solutions to 15 selected market challenges, in the frame of the S3E REVERSE Program.
📃 Press Release S3E Open Call #1 Reverse for solvers 📃
The consortium of S3E – Southern European Entrepreneurship Engine has officially launched the S3E Reverse for Solvers Open Call #1 targeting scaling start-ups and SMEs with deep tech solutions. Through S3E REVERSE, the project creates an Innovation and Technology Brokerage Program aiming at connecting corporates and public organisations (Challenge Organisations) with scale-ups, start-ups and SMEs (Solvers) that can address the identified challenges through their products, services, and solutions, based on deep tech and aligned to the Sustainable Development Goals (SDGs).
The Open Call for Solvers will be available from 14 March (12.00 pm CET) until 15 May (17.00 pm CET).
The Solvers - SMEs and more mature start-ups - are invited to join the program, submitting their solutions, ideas and products that solve one or more of the 15 identified challenges. These challenges were unveiled by 19 Challenge Organisations since last November 2022 at the first stage of the S3E REVERSE program and reviewed by S3E partners in collaboration with external experts. All of them have the highest degree of potential, impact, innovation, and feasibility and should be addressed through deep tech solutions. Check the selected challenges here.
Who can apply?
Scaling Start-ups and SMEs with deep tech projects and solutions from all Southern Europe, meeting the following criteria:
- Is established in any country of the Southern European science-based innovation ecosystem is eligible for the Horizon Europe program including associated countries.
- Is capable of addressing a challenge that has been submitted as part of the conducted open call for Challenges and which is related to the 17 Sustainable Development Goals.
- Can justify the development and / or deployment of a Deep Tech solution.
How to apply?
Interested start-ups and SMEs tackling the challenges can apply before 15 May 2023 via F6S and find further information about the application guidelines here. The S3E REVERSE Open Call for Solvers will operate on a ‘first come – first Served’ for the solvers: when a match is identified, the challenge provider organisation and the solver can start working together immediately.
What are the benefits?
- Innovation Readiness Assessment: a Self-assessment of the solver that will help thecompany identify weak points or problems in their growth. Our Technology brokers can then suggest specific actions that can help the solver improve their operations.
- Mentoring (from selected business & innovation experts) based on an assessment of the company that will help the scale-up identify any weak points of problems in their growth scale.
- Coaching (from sustainability experts) will support the company in identifying business cases and potential applications based on their portfolio that could provide solutions to
address sustainability challenges related to the UN SDG of the call. - Training in public procurement, including Pre-Commercial Procurement and Public Procurement for Innovative solutions (PPIs) that will help scale-ups access bigger projects and clients.
- Masterclasses with established experts in their field in topics such as ESG compliance, leadership, onboarding new personnel, customer acquisition, company culture).
- Networking with industry leaders and showcase opportunities at the S3E Open day.
- Technology Brokerage: our technology brokers will help the SMEs and startups prepare their technical offer and match them with the challenge organisations in need.
Join the South European DeepTech Revolution!
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